| Name | Alias(es) | Type | Subtype | Isolation Date | Isolation | Origin | Author | Notes |
| 1260 | MS-DOS | 1990 | Mark Washburn, Ralf Burger | First virus to use polymorphic encryption | ||||
| 4K | 4096 | MS-DOS | January 1990 | unknown | The first virus to use stealth | |||
| 5lo | MS-DOS | October 1992 | unknown | Infects .EXE files only |
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